WebNov 10, 2024 · In the study, we found that duck TRIM25 can induce the production of IFN-β against double-stranded RNA virus stimuli and that the SPRY domain of duTRIM25 was … WebAug 2, 2016 · TRIM25 belongs to the tripartite motif (TRIM) protein family, which is characterized by a conserved domain organization at the N terminus (known as the TRIM or RBCC motif) composed of a catalytic RING domain, one or two B-box domains, and a coiled-coil dimerization domain ( Meroni and Diez-Roux, 2005; Figure 1 A).

RNA-binding activity of TRIM25 is mediated by its …

WebTripartite motif (TRIM) family or RBCC proteins comprises characteristic zinc‐binding domains (a RING (R), a B‐box type 1 (B1) and a B‐box type 2 (B2)… WebMar 21, 2024 · The crystal structure of TRIM72 B-box-coiled-coil-SPry domains (BCC-SPRY) is presented, revealing the molecular basis ofTRIM72 oligomerization, which is closely linked to disulfide bond formation and demonstrating that TRIM 72 interacts with several kinds of negatively charged lipids in addition to phosphatidylserine. Tripartite Motif Protein 72 … chris holder facebook

UniProt

WebFeb 22, 2024 · To manage associated domains and accounts: Sign in to the Zoom web portal. In the navigation panel, click Account Management then Account Profile. Click the … WebFinally, we show that the effect of PB1-F2 on mitochondria abrogates TRIM25-mediated ubiquitination of RIG-I CARD in both human and avian cells, while an NS1 variant from the PR8 influenza virus strain does not. ... the PRY/SPRY domain fragment of duck TRIM27-L , suggesting a specific interaction (Figure 4E). WebTRIM25 is a member of the PRY/SPRY domain subfamily and the first member of this subgroup for which RNA binding has been observed (7,14-16). TRIM25 has reported functions in innate immunity, morphogenesis and cell proliferation (17-21), but mechanistic understanding of its mode of action is scarce. geo bathroom panels