WebOct 19, 2024 · A few of these drugs include the anti-seizure drugs carbamazepine and valproic acid, the anti-gout drug rasburicase, and the immunosuppressive drug azathioprine. A large range of drugs... WebSome drugs that have a narrow therapeutic index are: Warfarin Lithium Digoxin Phenytoin Gentamicin Amphotericin B 5-fluorouracil AZT (Zidovudine) Care must be taken to determine the right dose for the aforementioned drugs in individual cases, as administration of large doses could cause adverse effects.
Are Some People More Sensitive to Drug Side Effects?
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CEP 261 Quiz 2 Flashcards Chegg.com
WebMar 22, 2024 · Narcotic drugs can be incredibly dangerous and have a high risk for potentially life-threatening overdose. More than 42,000 opioid-related deaths were … WebMargin of safety for each drug/biologic product. If one or more of the drugs/biologics has a narrow margin of safety (i.e., causes serious toxicity at exposures close to the WebNov 12, 2024 · Application of a Safety Factor • Determine the HED of a NOAEL in the most appropriate species, then apply a safety factor to provide a margin of safety for human volunteers • Allows for: • Enhanced sensitivity in humans to the toxicity associated with a drug • Varied bioavailability across species barbarian on hulu