CYTARABINE (sye-tare'a-been) ARA-C, Cytosar-U, Cytosine Arabinoside, DepoCyt, Tarabine Classifications:antineoplastic; antimetabolite, purine antagonist; immunosuppressant Prototype: 6-mercaptopurine Pregnancy Category: D Availability 10 mg/mL liposomal, 20 mg/mL, 100 mg, 500 mg, 1g, 2 g injection … See more Pyrimidine analog with cell phase specificity affecting rapidly dividing cells in S phase (DNA synthesis). In certain conditions prevents development of cell from G1to S phase. Interferes with DNA and RNA synthesis. See more To induce and maintain remission in acute myelocytic leukemia, acute lymphocytic leukemia, and meningeal leukemia and for treatment of lymphomas. Used in combination with other antineoplastics in established … See more Antineoplastic agent which has strong myelosuppressant activity. Immunosuppressant properties are exhibited by obliterated cell-mediated immune responses, such as delayed hypersensitivity skin … See more History of drug-induced myelosuppression; immunization procedures; pregnancy (category D) particularly during first trimester, lactation. … See more WebK R Rai, J F Holland, O J Glidewell, V Weinberg, K Brunner, J P Obrecht, H D Preisler, I W Nawabi, D Prager, R W Carey, M R Cooper, F Haurani, J L Hutchison, R T Silver, G …
Optimal dosing of cytarabine in induction and post …
WebJan 5, 2007 · Liposomal cytarabine (Enzon Pharmaceuticals, Piscataway, NJ; Skye Pharma, San Diego, CA), an intrathecal (IT) preparation of cytarabine with a prolonged … http://www.robholland.com/Nursing/Drug_Guide/data/monographframes/C126.html good christmas presents for husbands
Cytarabine - NCI - National Cancer Institute
WebApr 6, 2024 · General: Only physicians experienced in cancer chemotherapy should use cytarabine. Warnings: Haematologic Effects: Cytarabine is a potent bone marrow suppressant; the severity depends on the dose of the drug and the schedule of administration.Therapy should be started cautiously in patients with pre-existing drug … WebApr 26, 2024 · Cytarabine may be used alone or in combination with other antineoplastic agents. It is indicated alone or in combination for induction of remission and/or maintenance in patients with acute myeloid leukaemia, acute non-lymphoblastic leukaemias, acute lymphoblastic leukaemias, acute lymphocytic leukaemia, erythroleukaemia, blast crises … WebAug 12, 2024 · Cytarabine is a pyrimidine analog and is also known as arabinosylcytosine (ARA-C). It is converted into the triphosphate form within the cell and competes with cytidine to incorporate itself into the DNA. The sugar moiety of cytarabine hinders the rotation of the molecule within the DNA. health ministry pdf