Ctgf ligament
WebFull length CTGF can be proteolytically cleaved in certain tissues to yield N-terminal truncated isoforms, which, depending on the isoform, contain only the TSP type I and … WebSep 17, 2024 · Cell–cell communication is an essential process to respond to biological stimuli and sustain the micro environmental homeostasis of human periodontal ligament stem cells (hPDLSCs). Connective tissue growth factor (CTGF), a critical secreted matrix protein, exhibits significant tasks in regulating the cell-cell and cell-matrix interactions.
Ctgf ligament
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WebDec 1, 2024 · Connective tissue growth factor (CTGF), also known as CCN2, is a member of the CCN family and is a secreted matricellular and multifunctional protein. ... China) and washed 10 times with PBS (pH 7.2) under sterile conditions. Then, the periodontal ligament tissues attached to the middle third of the roots were curetted … WebDec 4, 2009 · Since fibrosis is observed in smokers’ gingiva, it was hypothesized that fibrosis was caused by nicotine in the periodontium. Therefore, in this study, we investigated the effects of nicotine on the induction of a profibrotic molecule, connective tissue growth factor (CCN2/CTGF), in human gingival fibroblasts (HGFs) and periodontal ligament …
WebOct 13, 2024 · Connective tissue growth factor (CTGF) is a cysteine-rich peptide that exhibits platelet-derived growth factor (PDGF)-like biological and immunological … WebJun 1, 2004 · Skin ligaments (SL) (L. retinacula cutis) are present extensively in the face, hands, feet, and in breast tissue, but have seldom been reported elsewhere in the body. The traditional histological ...
WebCCN (for CYR61/ CTGF /NOV) proteins were identified originally from diverse cellular contexts and studied for their growth-promoting activities. It is now known that there are … WebJun 6, 2014 · Appropriate mechanical loading during occlusion and mastication play an important role in maintaining the homeostasis of periodontal ligament (PDL) tissue. Connective tissue growth factor (CTGF/CCN2), a matricellular protein, is known to upregulate extracellular matrix production, including collagen in PDL tissue.
WebApr 1, 2015 · Connective tissue growth factor (CTGF) is a downstream mediator of TGF-β. This study explores the effects of EMD and TGF-β1 on CTGF in periodontal ligament (PDL) fibroblasts and their interactions in PDL proliferation and development. Methods: Human PDL cells were stimulated with EMD. To explore the effects of EMD and TGF-β1 …
WebJun 3, 2011 · Abstract. Highlights: {yields} CCN2/CTGF localizes to the ligament-to-bone interface, but is not to the midsubstance region of human anterior cruciate ligament (ACL). {yields} Mechanical stretch induces higher increase of CCN2/CTGF gene expression and protein secretion in ACL interface cells compared with ACL midsubstance cells. {yields} … birds of a feather flickrWebOct 5, 2005 · Important roles of CCN2/CTGF in the development and regeneration of periodontal tissue including theperiodontal ligament are suggested. BackgroundCCN2/CTGF is known to be involved in tooth germ development and periodontal tissue remodeling, as well as in mesenchymal tissue development and regeneration. In … dan brown race the pale horseWebJun 29, 2024 · Objective . This work is aimed at revealing the role and the molecular mechanism of connective tissue growth factor 2 (CTGF) in the osteoblast differentiation … birds of a feather filming locationsWebJun 3, 2011 · In addition, CCN2/CTGF is known to stimulate cellular differentiation and ECM synthesis as well in these cells [5], [6], [7]. However, the expression pattern and function of CCN2/CTGF in human ligament tissues remain unclear. Anterior cruciate ligament (ACL) injuries usually occur in the femoral attachment of ACL that contains interface cells [8]. dan brown pointing out the great wayWebConnective tissue growth factor (CTGF) is covalently bound to latent TGFβ and is sequestered in the pericellular matrix (PCM) on heparan sulfate. ... At 10 weeks, surgical destabilisation of the joint, by cutting the … dan brown rubik\u0027s cubedan brown proximo libroWebJul 23, 2024 · The overall impact of ASCs and CTGF on early tendon healing response. The overall healing response was grossly compared among tendons from three repair groups … birds of a feather flock together images